mouse PIK3AP1 shRNA silencing AAV

Cat. No: shAAV-268637

Availability: 6-8 weeks

Name: AAV-m-PIK3AP1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Pik3ap1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Pik3ap1
Gene Name: phosphoinositide-3-kinase adaptor protein 1
Gene ID: 83490
Gene Synonyms: 1810044J04Rik; BCAP
ORF Size: 2439 bp
RefSeq#: NM_031376
Gene Description: Involved in the activation of phosphoinositide 3-kinase (PI3K) in B-cells and in natural killer (NK) cells. Couples B-cell antigen receptor (BCR) to PI3K activation by providing a docking site for the PI3K subunit PIK3R1, which contributes to B-cell development. Seems to have a complementary role with CD19 in PI3K activation (By similarity). May be involved in the survival of mature B-cells via activation of REL (By similarity).
UniGene ID: Mm.222266