mouse PFN1 shRNA silencing AAV

Cat. No: shAAV-268450

Availability: Immediate

Name: AAV-m-PFN1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Pfn1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Pfn1
Gene Name: profilin 1
Gene ID: 18643
Gene Synonyms: Pfn
ORF Size: 423 bp
RefSeq#: NM_011072
Gene Description: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.
UniGene ID: Mm.2647