mouse PATL1 shRNA silencing AAV

Cat. No: shAAV-268100

Availability: 4-5 weeks

Name: AAV-m-PATL1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Patl1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Patl1
Gene Name: protein associated with topoisomerase II homolog 1 (yeast)
Gene ID: 225929
Gene Synonyms: AV312086; Pat1b
ORF Size: 2313 bp
RefSeq#: NM_172635
Gene Description: RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly. In case of infection, required for translation and replication of hepatitis C virus (HCV).
UniGene ID: Mm.42711