mouse PAM shRNA silencing AAV

Cat. No: shAAV-268027

Availability: 4-5 weeks

Name: AAV-m-PAM-shRNA

This is an AAV expressing shRNA for silencing of Mouse Pam.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Pam
Gene Name: peptidylglycine alpha-amidating monooxygenase
Gene ID: 18484
Gene Synonyms: PHM
ORF Size: 2937 bp
RefSeq#: NM_013626
Gene Description: Bifunctional enzyme that catalyzes 2 sequential steps in C-terminal alpha-amidation of peptides. The monooxygenase part produces an unstable peptidyl(2-hydroxyglycine) intermediate that is dismutated to glyoxylate and the corresponding desglycine peptide amide by the lyase part. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity.
UniGene ID: Mm.441453