mouse PACRG shRNA silencing AAV

Cat. No: shAAV-267984

Availability: 6-8 weeks

Name: AAV-m-PACRG-shRNA

This is an AAV expressing shRNA for silencing of Mouse Pacrg.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Pacrg
Gene Name: PARK2 co-regulated
Gene ID: 69310
Gene Synonyms: 1700008H23Rik
ORF Size: 726 bp
RefSeq#: NM_027032
Gene Description: Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease.
UniGene ID: Mm.18889