mouse NR3C2 shRNA silencing AAV

Cat. No: shAAV-266055

Availability: 6-8 weeks

Name: AAV-m-NR3C2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Nr3c2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Nr3c2
Gene Name: nuclear receptor subfamily 3, group C, member 2
Gene ID: 110784
Gene Synonyms: Mlr; MR
ORF Size: 2943 bp
RefSeq#: NM_001083906
Gene Description: Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
UniGene ID: Mm.324393