mouse NR3C1 shRNA silencing AAV

Cat. No: shAAV-266053

Availability: Immediate

Name: AAV-m-NR3C1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Nr3c1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Nr3c1
Gene Name: nuclear receptor subfamily 3, group C, member 1
Gene ID: 14815
Gene Synonyms: GR; Grl-1; Grl1
ORF Size: 2352 bp
RefSeq#: NM_008173
Gene Description: Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. Involved in nuclear translocation (By similarity).
UniGene ID: Mm.129481