mouse NR1H2 shRNA silencing AAV

Cat. No: shAAV-266034

Availability: 4-5 weeks

Name: AAV-m-NR1H2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Nr1h2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Nr1h2
Gene Name: nuclear receptor subfamily 1, group H, member 2
Gene ID: 22260
Gene Synonyms: AI194859; LXR; LXRB; LXRbeta; LXRBSV; NER1; OR-1; RIP15; Unr; Unr2; UR
ORF Size: 1341 bp
RefSeq#: NM_009473
Gene Description: Orphan receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8 (By similarity).
UniGene ID: Mm.968