mouse NOS3 shRNA silencing AAV

Cat. No: shAAV-265940

Availability: 6-8 weeks

Name: AAV-m-NOS3-shRNA

This is an AAV expressing shRNA for silencing of Mouse Nos3.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Nos3
Gene Name: nitric oxide synthase 3, endothelial cell
Gene ID: 18127
Gene Synonyms: 2310065A03Rik; ecNOS; eNOS; Nos-3
ORF Size: 3609 bp
RefSeq#: NM_008713
Gene Description: Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets|Function: Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may downregulate eNOS activity by forming heterodimers with isoform 1.
UniGene ID: Mm.258415