mouse NCKIPSD shRNA silencing AAV

Cat. No: shAAV-265513

Availability: 4-5 weeks

Name: AAV-m-NCKIPSD-shRNA

This is an AAV expressing shRNA for silencing of Mouse Nckipsd.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Nckipsd
Gene Name: NCK interacting protein with SH3 domain
Gene ID: 80987
Gene Synonyms: AF3P21; DIP1; ORF1; SPIN90; Wasbp; WASLBP; WISH
ORF Size: 2145 bp
RefSeq#: NM_030729
Gene Description: Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1). Induces microspike formation, in vivo (By similarity). In vitro, stimulates N-WASP-induced ARP2/3 complex activation in the absence of CDC42 (By similarity). May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion.
UniGene ID: Mm.192416