mouse MYD116 shRNA silencing AAV

Cat. No: shAAV-265268

Availability: 4-5 weeks

Name: AAV-m-MYD116-shRNA

This is an AAV expressing shRNA for silencing of Mouse Ppp1r15a.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Ppp1r15a
Gene Name: protein phosphatase 1, regulatory (inhibitor) subunit 15A
Gene ID: 17872
Gene Synonyms: 9630030H21; Gadd34; Myd116
ORF Size: 1974 bp
RefSeq#: NM_008654
Gene Description: Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.
UniGene ID: Mm.4048