mouse MX1 shRNA silencing AAV

Cat. No: shAAV-265227

Availability: 6-8 weeks

Name: AAV-m-MX1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Mx1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Mx1
Gene Name: MX dynamin-like GTPase 1
Gene ID: 17857
Gene Synonyms: AI893580; Mx; Mx-1
ORF Size: 1896 bp
RefSeq#: NM_010846
Gene Description: Dynamin-like GTPase acting as a cell-autonomous host restriction factor against many viral pathogens. Shows activity against influenza viruses, rhabdovirus VSV, bunyavirus LACV, Thogoto virus, measles virus, Hantaan virus, Coxsackie virus CVB, Rift Valley fever virus RVFV, hepatitis B virus HBV, and Crimean-Congo hemorrhagic fever virus CCHFV|Function: May regulate the calcium channel activity of TRPCs. Ring-like assemblies may induce membrane tubulation.
UniGene ID: Mm.33996