mouse MUL1 shRNA silencing AAV

Cat. No: shAAV-265196

Availability: 4-5 weeks

Name: AAV-m-MUL1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Mul1.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Mul1
Gene Name: mitochondrial ubiquitin ligase activator of NFKB 1
Gene ID: 68350
Gene Synonyms: 0610009K11Rik; AV000801; Gide
ORF Size: 1059 bp
RefSeq#: NM_026689
Gene Description: Exhibits weak E3 ubiquitin-protein ligase activity, but preferentially acts as a SUMO E3 ligase at physiological concentrations. Plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
UniGene ID: Mm.103413