mouse MTAP1B shRNA silencing AAV

Cat. No: shAAV-265092

Availability: 4-5 weeks

Name: AAV-m-MTAP1B-shRNA

This is an AAV expressing shRNA for silencing of Mouse Map1b.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Map1b
Gene Name: microtubule-associated protein 1B
Gene ID: 17755
Gene Synonyms: A230055D22; AI843217; LC1; MAP5; Mtap-5; Mtap1b; Mtap5
ORF Size: 7395 bp
RefSeq#: NM_008634
Gene Description: Facilitates tyrosination of alpha-tubulin in neuronal microtubules (By similarity). Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B Binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing.
UniGene ID: Mm.474896