mouse MTAP shRNA silencing AAV

Cat. No: shAAV-265091

Availability: 4-5 weeks

Name: AAV-m-MTAP-shRNA

This is an AAV expressing shRNA for silencing of Mouse Mtap.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Mtap
Gene Name: methylthioadenosine phosphorylase
Gene ID: 66902
Gene Synonyms: 1300019I21Rik; MSAP
ORF Size: 852 bp
RefSeq#: NM_024433
Gene Description: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
UniGene ID: Mm.28500