mouse MSX2 shRNA silencing AAV

Cat. No: shAAV-265079

Availability: 6-8 weeks

Name: AAV-m-MSX2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Msx2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Msx2
Gene Name: msh homeobox 2
Gene ID: 17702
Gene Synonyms: BB122635; Hox-8; Hox8; Hox8.1
ORF Size: 804 bp
RefSeq#: NM_013601
Gene Description: Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antogonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter.
UniGene ID: Mm.1763