mouse MMP9 shRNA silencing AAV

Cat. No: shAAV-264748

Availability: 6-8 weeks

Name: AAV-m-MMP9-shRNA

This is an AAV expressing shRNA for silencing of Mouse Mmp9.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Mmp9
Gene Name: matrix metallopeptidase 9
Gene ID: 17395
Gene Synonyms: AW743869; B/MMP9; Clg4b; Gel B; MMP-9; pro-MMP-9
ORF Size: 2193 bp
RefSeq#: NM_013599
Gene Description: MMP9 may play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly- -Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.
UniGene ID: Mm.4406