mouse MMP17 shRNA silencing AAV

Cat. No: shAAV-264724

Availability: 4-5 weeks

Name: AAV-m-MMP17-shRNA

This is an AAV expressing shRNA for silencing of Mouse Mmp17.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Mmp17
Gene Name: matrix metallopeptidase 17
Gene ID: 23948
Gene Synonyms: MT4-MMP; MT4MMP; MTMMP4
ORF Size: 1737 bp
RefSeq#: NM_011846
Gene Description: Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.
UniGene ID: Mm.42047