mouse MCL1 shRNA silencing AAV

Cat. No: shAAV-264366

Availability: 4-5 weeks

Name: AAV-m-MCL1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Mcl1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Mcl1
Gene Name: myeloid cell leukemia sequence 1
Gene ID: 17210
Gene Synonyms: AW556805; Mcl-1
ORF Size: 996 bp
RefSeq#: NM_008562
Gene Description: Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
UniGene ID: Mm.1639