mouse MADCAM1 shRNA silencing AAV

Cat. No: shAAV-264073

Availability: 6-8 weeks

Name: AAV-m-MADCAM1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Madcam1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Madcam1
Gene Name: mucosal vascular addressin cell adhesion molecule 1
Gene ID: 17123
Gene Synonyms: AV211525
ORF Size: 786 bp
RefSeq#: NM_013591
Gene Description: Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.
UniGene ID: Mm.391556