mouse LRRFIP1 shRNA silencing AAV

Cat. No: shAAV-263892

Availability: 4-5 weeks

Name: AAV-m-LRRFIP1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Lrrfip1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Lrrfip1
Gene Name: leucine rich repeat (in FLII) interacting protein 1
Gene ID: 16978
Gene Synonyms: AU024550; Fliiap1
ORF Size: 1992 bp
RefSeq#: NM_008515
Gene Description: Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
UniGene ID: Mm.395990