mouse LPIN1 shRNA silencing AAV

Cat. No: shAAV-263781

Availability: 4-5 weeks

Name: AAV-m-LPIN1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Lpin1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Lpin1
Gene Name: lipin 1
Gene ID: 14245
Gene Synonyms: 4631420P06; fld; Kiaa0188; Lipin1; mKIAA0188
ORF Size: 2775 bp
RefSeq#: NM_172950
Gene Description: Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A/PPARA to modulate lipid metabolism gene expression (By similarity). Is involved in adipocyte differentiation. May also be involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol (By similarity).
UniGene ID: Mm.153625