mouse LIN54 shRNA silencing AAV

Cat. No: shAAV-263466

Availability: 4-5 weeks

Name: AAV-m-LIN54-shRNA

This is an AAV expressing shRNA for silencing of Mouse Lin54.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Lin54
Gene Name: lin-54 homolog (C. elegans)
Gene ID: 231506
Gene Synonyms: AI461788
ORF Size: 1260 bp
RefSeq#: NM_172714
Gene Description: Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. In G0 phase, the complex binds to more than 800 promoters and is required for repression of E2F target genes. In S phase, the complex selectively binds to the promoters of G2/M genes whose products are required for mitosis and participates in their cell cycle dependent activation. In the complex, acts as a DNA-binding protein that binds the promoter of CDK1 in a sequence-specific manner.
UniGene ID: Mm.212568