mouse LEP shRNA silencing AAV

Cat. No: shAAV-263379

Availability: 6-8 weeks

Name: AAV-m-LEP-shRNA

This is an AAV expressing shRNA for silencing of Mouse Lep.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Lep
Gene Name: leptin
Gene ID: 16846
Gene Synonyms: ob; obese
ORF Size: 504 bp
RefSeq#: NM_008493
Gene Description: LEP may function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
UniGene ID: Mm.277072