mouse KHDRBS3 shRNA silencing AAV

Cat. No: shAAV-262786

Availability: 4-5 weeks

Name: AAV-m-KHDRBS3-shRNA

This is an AAV expressing shRNA for silencing of Mouse Khdrbs3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Khdrbs3
Gene Name: KH domain containing, RNA binding, signal transduction associated 3
Gene ID: 13992
Gene Synonyms: Etle; Salp; SLM-2; Slm2; T-STAR
ORF Size: 1041 bp
RefSeq#: NM_010158
Gene Description: RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. May play a role as a negative regulator of cell growth. Inhibits cell proliferation. Involved in splice site selection of vascular endothelial growth factor. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. Involved in post-transcriptional regulation of HIV-1 gene expression. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro.
UniGene ID: Mm.17964