mouse KCNE1 shRNA silencing AAV

Cat. No: shAAV-262619

Availability: 6-8 weeks

Name: AAV-m-KCNE1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Kcne1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Kcne1
Gene Name: potassium voltage-gated channel, Isk-related subfamily, member 1
Gene ID: 16509
Gene Synonyms: Isk; MinK; nmf190
ORF Size: 390 bp
RefSeq#: NM_008424
Gene Description: Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr).
UniGene ID: Mm.299425