mouse IRS1 shRNA silencing AAV

Cat. No: shAAV-262382

Availability: Immediate

Name: AAV-m-IRS1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Irs1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Irs1
Gene Name: insulin receptor substrate 1
Gene ID: 16367
Gene Synonyms: G972R; IRS-1
ORF Size: 3693 bp
RefSeq#: NM_010570
Gene Description: IRS1 may mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).
UniGene ID: Mm.476433