mouse IL1RN shRNA silencing AAV

Cat. No: shAAV-262146

Availability: 4-5 weeks

Name: AAV-m-IL1RN-shRNA

This is an AAV expressing shRNA for silencing of Mouse Il1rn.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Il1rn
Gene Name: interleukin 1 receptor antagonist
Gene ID: 16181
Gene Synonyms: F630041P17Rik; IL-1ra
ORF Size: 480 bp
RefSeq#: NM_031167
Gene Description: Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure.
UniGene ID: Mm.882