mouse HOMER2 shRNA silencing AAV

Cat. No: shAAV-261547

Availability: 4-5 weeks

Name: AAV-m-HOMER2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Homer2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Homer2
Gene Name: homer scaffolding protein 2
Gene ID: 26557
Gene Synonyms: 9330120H11Rik; AW539445; CPD; Vesl-2
ORF Size: 1062 bp
RefSeq#: NM_011983
Gene Description: Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses.
UniGene ID: Mm.228