mouse HMOX2 shRNA silencing AAV

Cat. No: shAAV-261488

Availability: 4-5 weeks

Name: AAV-m-HMOX2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Hmox2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Hmox2
Gene Name: heme oxygenase 2
Gene ID: 15369
Gene Synonyms: HO-2; HO2
ORF Size: 948 bp
RefSeq#: NM_010443
Gene Description: Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.
UniGene ID: Mm.272866