mouse HIP1 shRNA silencing AAV

Cat. No: shAAV-261304

Availability: 6-8 weeks

Name: AAV-m-HIP1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Hip1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Hip1
Gene Name: huntingtin interacting protein 1
Gene ID: 215114
Gene Synonyms: 2610109B09Rik; A930014B11Rik; E130315I21Rik; mKIAA4113
ORF Size: 2721 bp
RefSeq#: NM_146001
Gene Description: Plays a role in clathrin-mediated endocytosis and trafficking. Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. Enhances androgen receptor (AR)-mediated transcription. May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. May play a functional role in the cell filament networks. May be required for differentiation, proliferation, and/or survival of somatic and germline progenitors.
UniGene ID: Mm.280805