mouse HDAC5 shRNA silencing AAV

Cat. No: shAAV-261178

Availability: 4-5 weeks

Name: AAV-m-HDAC5-shRNA

This is an AAV expressing shRNA for silencing of Mouse Hdac5.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Hdac5
Gene Name: histone deacetylase 5
Gene ID: 15184
Gene Synonyms: AI426555; Hdac4; mHDA1; mKIAA0600
ORF Size: 3345 bp
RefSeq#: NM_010412
Gene Description: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors.
UniGene ID: Mm.22665