mouse H47 shRNA silencing AAV

Cat. No: shAAV-261077

Availability: 4-5 weeks

Name: AAV-m-H47-shRNA

This is an AAV expressing shRNA for silencing of Mouse Selenos.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Selenos
Gene Name: selenoprotein S
Gene ID: 109815
Gene Synonyms: 1500011E07Rik; C78786; H-4; H-47; H4; H47; Sels; Vimp
ORF Size: 567 bp
RefSeq#: NM_024439
Gene Description: Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination.
UniGene ID: Mm.22362