mouse H2AFZ shRNA silencing AAV

Cat. No: shAAV-261064

Availability: Immediate

Name: AAV-m-H2AFZ-shRNA

This is an AAV expressing shRNA for silencing of Mouse H2afz.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: H2afz
Gene Name: H2A histone family, member Z
Gene ID: 51788
Gene Synonyms: H2A.Z; H2a.z-1
ORF Size: 387 bp
RefSeq#: NM_016750
Gene Description: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.
UniGene ID: Mm.465508