mouse GRIK1 shRNA silencing AAV

Cat. No: shAAV-260760

Availability: 6-8 weeks

Name: AAV-m-GRIK1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Grik1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Grik1
Gene Name: glutamate receptor, ionotropic, kainate 1
Gene ID: 14805
Gene Synonyms: A830007B11Rik; D16Ium24; D16Ium24e; GluK1; GluK5; Glur-5; Glur5; Glurbeta1
ORF Size: 2499 bp
RefSeq#: NM_146072
Gene Description: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus.
UniGene ID: Mm.5134