mouse GPR68 shRNA silencing AAV

Cat. No: shAAV-260656

Availability: 6-8 weeks

Name: AAV-m-GPR68-shRNA

This is an AAV expressing shRNA for silencing of Mouse Gpr68.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Gpr68
Gene Name: G protein-coupled receptor 68
Gene ID: 238377
Gene Synonyms: BB131428; Ogr1
ORF Size: 1098 bp
RefSeq#: NM_175493
Gene Description: Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer (By similarity).
UniGene ID: Mm.32160