mouse GPHN shRNA silencing AAV

Cat. No: shAAV-260516

Availability: Immediate

Name: AAV-m-GPHN-shRNA

This is an AAV expressing shRNA for silencing of Mouse Gphn.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Gphn
Gene Name: gephyrin
Gene ID: 268566
Gene Synonyms: 5730552E08Rik; AI662856; BC027112; C230040D23; geph; GPH; GPHRYN
ORF Size: 2319 bp
RefSeq#: NM_172952
Gene Description: Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules (By similarity). Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
UniGene ID: Mm.453131