mouse GOPC shRNA silencing AAV

Cat. No: shAAV-260459

Availability: 4-5 weeks

Name: AAV-m-GOPC-shRNA

This is an AAV expressing shRNA for silencing of Mouse Gopc.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Gopc
Gene Name: golgi associated PDZ and coiled-coil motif containing
Gene ID: 94221
Gene Synonyms: 2210402P09Rik; AI844555; CAL; FIG; GOPC1; PIST
ORF Size: 1368 bp
RefSeq#: NM_053187
Gene Description: Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels. May also regulate the intracellular trafficking of the ADR1B receptor. May play a role in autophagy. Overexpression results in CFTR intracellular retention and degradation in the lysosomes.
UniGene ID: Mm.390258