mouse GLRX3 shRNA silencing AAV

Cat. No: shAAV-260207

Availability: 4-5 weeks

Name: AAV-m-GLRX3-shRNA

This is an AAV expressing shRNA for silencing of Mouse Glrx3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Glrx3
Gene Name: glutaredoxin 3
Gene ID: 30926
Gene Synonyms: PICOT; Txnl2
ORF Size: 1014 bp
RefSeq#: NM_023140
Gene Description: Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity.
UniGene ID: Mm.267692