mouse GADD45GIP1 shRNA silencing AAV

Cat. No: shAAV-259830

Availability: 4-5 weeks

Name: AAV-m-GADD45GIP1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Gadd45gip1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Gadd45gip1
Gene Name: growth arrest and DNA-damage-inducible, gamma interacting protein 1
Gene ID: 102060
Gene Synonyms: 2310040G17Rik; AI425883; Crif1; MRP-L59; Plinp1
ORF Size: 669 bp
RefSeq#: NM_183358
Gene Description: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity.
UniGene ID: Mm.255539