mouse GABRP shRNA silencing AAV

Cat. No: shAAV-259817

Availability: 6-8 weeks

Name: AAV-m-GABRP-shRNA

This is an AAV expressing shRNA for silencing of Mouse Gabrp.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Gabrp
Gene Name: gamma-aminobutyric acid (GABA) A receptor, pi
Gene ID: 216643
ORF Size: 1323 bp
RefSeq#: NM_146017
Gene Description: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. In the uterus, the function of the receptor appears to be related to tissue contractility. The binding of this pI subunit with other GABA(A) receptor subunits alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone.
UniGene ID: Mm.99989