mouse GAB2 shRNA silencing AAV

Cat. No: shAAV-259778

Availability: 6-8 weeks

Name: AAV-m-GAB2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Gab2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Gab2
Gene Name: growth factor receptor bound protein 2-associated protein 2
Gene ID: 14389
Gene Synonyms: AI463667; D130058I17Rik; p97
ORF Size: 1998 bp
RefSeq#: NM_010248
Gene Description: Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
UniGene ID: Mm.42033