mouse FRZB shRNA silencing AAV

Cat. No: shAAV-259652

Availability: 4-5 weeks

Name: AAV-m-FRZB-shRNA

This is an AAV expressing shRNA for silencing of Mouse Frzb.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Frzb
Gene Name: frizzled-related protein
Gene ID: 20378
Gene Synonyms: frezzled; fritz; Frp; frzb-1; Sfrp3
ORF Size: 972 bp
RefSeq#: NM_011356
Gene Description: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.
UniGene ID: Mm.427436