mouse FPR2 shRNA silencing AAV

Cat. No: shAAV-259618

Availability: 6-8 weeks

Name: AAV-m-FPR2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Fpr2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Fpr2
Gene Name: formyl peptide receptor 2
Gene ID: 14289
Gene Synonyms: E330010I07Rik; Fpr-rs2
ORF Size: 1056 bp
RefSeq#: NM_008039
Gene Description: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).
UniGene ID: Mm.477887