mouse FOXD3 shRNA silencing AAV

Cat. No: shAAV-259559

Availability: 6-8 weeks

Name: AAV-m-FOXD3-shRNA

This is an AAV expressing shRNA for silencing of Mouse Foxd3.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Foxd3
Gene Name: forkhead box D3
Gene ID: 15221
Gene Synonyms: CWH3; Genesis; Hfh2
ORF Size: 1410 bp
RefSeq#: NM_010425
Gene Description: Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.
UniGene ID: Mm.4758