mouse FOS shRNA silencing AAV

Cat. No: shAAV-259549

Availability: Immediate

Name: AAV-m-FOS-shRNA

This is an AAV expressing shRNA for silencing of Mouse Fos.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Fos
Gene Name: FBJ osteosarcoma oncogene
Gene ID: 14281
Gene Synonyms: c-fos; cFos; D12Rfj1
ORF Size: 1143 bp
RefSeq#: NM_010234
Gene Description: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.
UniGene ID: Mm.246513