mouse FDPS shRNA silencing AAV

Cat. No: shAAV-259307

Availability: 4-5 weeks

Name: AAV-m-FDPS-shRNA

This is an AAV expressing shRNA for silencing of Mouse Fdps.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Fdps
Gene Name: farnesyl diphosphate synthetase
Gene ID: 110196
Gene Synonyms: 6030492I17Rik; AI256750; Fdpsl1; mKIAA1293
ORF Size: 1062 bp
RefSeq#: NM_134469
Gene Description: Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.
UniGene ID: Mm.39472