mouse FANCM shRNA silencing AAV

Cat. No: shAAV-259152

Availability: 4-5 weeks

Name: AAV-m-FANCM-shRNA

This is an AAV expressing shRNA for silencing of Mouse Fancm.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Fancm
Gene Name: Fanconi anemia, complementation group M
Gene ID: 104806
Gene Synonyms: AI427100; C730036B14Rik; D12Ertd364e
ORF Size: 6066 bp
RefSeq#: NM_178912
Gene Description: ATPase required for FANCD2 ubiquitination, a key reaction in DNA repair. Binds to ssDNA but not to dsDNA. Recruited to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions.
UniGene ID: Mm.374847