mouse ESRRA shRNA silencing AAV

Cat. No: shAAV-258720

Availability: 4-5 weeks

Name: AAV-m-ESRRA-shRNA

This is an AAV expressing shRNA for silencing of Mouse Esrra.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Esrra
Gene Name: estrogen related receptor, alpha
Gene ID: 26379
Gene Synonyms: Err1; ERRalpha; Estrra; Nr3b1
ORF Size: 1269 bp
RefSeq#: NM_007953
Gene Description: Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism.
UniGene ID: Mm.386776