mouse EIF3I shRNA silencing AAV

Cat. No: shAAV-258215

Availability: 4-5 weeks

Name: AAV-m-EIF3I-shRNA

This is an AAV expressing shRNA for silencing of Mouse Eif3i.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Eif3i
Gene Name: eukaryotic translation initiation factor 3, subunit I
Gene ID: 54709
Gene Synonyms: 36kDa; D4Ertd632e; Eif3s2; Trip1
ORF Size: 978 bp
RefSeq#: NM_018799
Gene Description: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
UniGene ID: Mm.250874